2003;6(2):121-128. For most people, pomegranates do not cause significant side effects. Part 182 -- Substances Generally Recognized As Safe. B., Takada, Y., Sand, D., and Heber, D. Pomegranate juice, total pomegranate ellagitannins, and punicalagin suppress inflammatory cell signaling in colon cancer cells. View abstract. View abstract. View abstract. Bioactive compounds from the seeds of Punica granatum (pomegranate). Uncontrolled Blood Sugar: How Dangerous Is It? Navarro, P. Nicolas T. S. Gabaldon J. Patel, C., Dadhaniya, P., Hingorani, L., and Soni, M. G. Safety assessment of pomegranate fruit extract: acute and subchronic toxicity studies. Kim, Y. H. and Choi, E. M. Stimulation of osteoblastic differentiation and inhibition of interleukin-6 and nitric oxide in MC3T3-E1 cells by pomegranate ethanol extract. Pande, G. and Akoh, C. C. Antioxidant capacity and lipid characterization of six Georgia-grown pomegranate cultivars. Jurenka, J. S. Therapeutic applications of pomegranate (Punica granatum L.): a review. View abstract. View abstract. Int J Impot.Res 2007;19(6):564-567. Kolekar, V. S. Wakure D. D. Raut P. N. and Utture S. C. Monitoring of pesticide residues in exportable pomegranate fruits. Jardini, F. A. Lima A. de Mendonça R. M. Z. Pinto R. J. Mancini D. A. P. and Mancini Filho J. Phenolic compounds from pulp and seeds of pomegranate (Punica granatum, L.): antioxidant activity and protection of MDCK cells. Endocr.Res. View abstract. Kelebek, H. and Canbas A. Organic acid, sugar and phenolic compounds and antioxidant capacity of Hicaz pomegranate juice. Shukla, M., Gupta, K., Rasheed, Z., Khan, K. A., and Haqqi, T. M. Consumption of hydrolyzable tannins-rich pomegranate extract suppresses inflammation and joint damage in rheumatoid arthritis. Does pomegranate intake attenuate cardiovascular risk factors in hemodialysis patients? 2009;28(2):184-195. Keep nutritious snack options on hand, such as veggies and dip, yogurt and nuts, and whole fruits. International Journal of Fruit Science 2009;9(3):226-231. Bhadbhade, S. J., Acharya, A. Orak, H. H. Evaluation of antioxidant activity, colour and some nutritional characteristics of pomegranate (Punica granatum L.) juice and its sour concentrate processed by conventional evaporation. J.Agric.Food Chem. Devatkal, S. K., Narsaiah, K., and Borah, A. Anti-oxidant effect of extracts of kinnow rind, pomegranate rind and seed powders in cooked goat meat patties. Obesity. Effect of pomegranate (Punica granatum) peels and it's extract on obese hypercholesterolemic rats. Integr.Biol.(Camb.) Hossin, F. L. A. The effects of pomegranate juice consumption on blood pressure and cardiovascular health. Kumar, S., Maheshwari, K. K., and Singh, V. Central nervous system activity of acute administration of ethanol extract of Punica granatum L. seeds in mice. View abstract. Expert Opin Drug Metab Toxicol 2008;4:381-93. 2009;60 Suppl 2:197-210. Athletic performance. View abstract. Khateeb, J., Gantman, A., Kreitenberg, A. J., Aviram, M., and Fuhrman, B. Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: a role for PPAR-gamma pathway. Like many areas in aromatherapy today, research on the subject of essential oils affecting birth control is scarce. Nishigaki, I. Rajendran P. Venugopal R. Ekambaram G. Sakthisekaran D. and Nishigaki Y. Effects of Quercus ilex L. and Punica granatum L. polyphenols against ethanol-induced gastric damage in rats. J Ethnopharmacol. Banerjee, K., Dasgupta, S., Jadhav, M. R., Naik, D. G., Ligon, A. P., Oulkar, D. P., Savant, R. H., and Adsule, P. G. A fast, inexpensive, and safe method for residue analysis of meptyldinocap in different fruits by liquid chromatography/tandem mass spectrometry. View abstract. Li Y, Wen S, Kota BP, et al. Lansky, E. P. and Newman, R. A. Punica granatum (pomegranate) and its potential for prevention and treatment of inflammation and cancer. View abstract. How Alcohol Can Affect Your Birth Control. 2009;72(12):2508-2516. View abstract. In Vitro and In Vivo Antibacterial Activity of Punica granatum Peel Ethanol Extract against Salmonella. View abstract. "If you do find depression exacerbated with the use of oral contraceptives, make sure to … View abstract. Seeram, N. P., Henning, S. M., Zhang, Y., Suchard, M., Li, Z., and Heber, D. Pomegranate juice ellagitannin metabolites are present in human plasma and some persist in urine for up to 48 hours. Basic report: 09286, pomegranates, raw. Indian J.Exp.Biol. 2019;29(2):201-208. By: Stacey Kole 21 December, 2017. View abstract. Rivara MB, Mehrotra R, Linke L, et al. does not impact your fertility. Altern.Med.Rev. Journal of Food Engineering 2010;99(1):16-23. Ferrara L, Schettino O, Forgione P, et al. Adverse reaction to pomegranate ingestion. Clinical Oncology Alert 2008;13(2):3-4. Lei F, Zhang XN, Wang W, et al. Diarrhea can affect birth control if it’s severe enough. A. Arzi A. Sistani N. K. and Mikaili P. The hydro-alcoholic extract of pomegranate seed has anti-inflammatory effects on formalin-induced inflammation in rat hind paw. Birth control has many side effects. 2010;35(1):1-16. 2011;91(12):2160-2165. Molecules. Rosuvastatin (Crestor) interacts with POMEGRANATE. View abstract. Study on wound healing activity of Punica granatum peel. View abstract. 3376 Share on Facebook. If you take birth control, you should discuss your sleep-aid options with your doctor. Journal of Pharmacy Research 2010;3(12):2850-2852. 2018;62(11):e1800160. Toxicol.Mech.Methods 2011;21(6):495-502. Heber, D. Multitargeted therapy of cancer by ellagitannins. J.Food Sci. 2008;46(8):2728-2735. Progestin doesn’t appear to provide the same beneficial effect. Mirmiran, P., Fazeli, M. R., Asghari, G., Shafiee, A., and Azizi, F. Effect of pomegranate seed oil on hyperlipidaemic subjects: a double-blind placebo-controlled clinical trial. 2009;11(8):710-715. View abstract. “I felt a little bit like I woke up from a nap. [Antiviral activity of tannin from the pericarp of Punica granatum L. against genital Herpes virus in vitro]. Balbir-Gurman A, Fuhrman B, Braun-Moscovici Y, et al. Your lifestyle and medical history can also change over time, which may affect your choices. Sahebkar A, Simental-Mendia LE, Giorgini P, Ferri C, Grassi D. Lipid profile changes after pomegranate consumption: a systematic review and meta-analysis of randomized controlled trials. Early research shows that drinking fresh pomegranate juice 1.5 mL/kg improves blood sugar in some people with diabetes. B. Antimicrobial screening of some Indian spices. Med.Sci.Sports Exerc. View abstract. Some medications are changed and broken down by the liver. Biofactors 2007;31(1):17-24. Allergy to pomegranate (Punica granatum). Turk G, Sonmez M, Aydin M, Yuce A, Gur S, Yuksel M, Aksu EH, and Aksoy H. Effects of pomegranate juice consumption on sperm quality, spermatogenic cell density, antioxidant activity and testosterone level in male rats. Pomegranate seems to decrease blood pressure. View abstract. Wright, H. and Pipkin F. B. Pomegranates (Punica granatum), kiwifruit (Actinidia deliciosa) and blood pressure: a pilot study. Zhang Y, Krueger D, Durst R, et al. Valsecchi R, Reseghetti A, Leghissa P, et al. View abstract. View abstract. J Agric Food Chem 2000;48:4581-9. pii: E721. Keep in mind: If you test one form of birth control, and you find it messes with your desire in undesired ways, you can stop what you’re on. Rosenblat, M., Volkova, N., Attias, J., Mahamid, R., and Aviram, M. Consumption of polyphenolic-rich beverages (mostly pomegranate and black currant juices) by healthy subjects for a short term increased serum antioxidant status, and the serum's ability to attenuate macrophage cholesterol accumulation. Yeo C, Shon J, Liu K, et al. The Herbal Alternatives for Menopause (HALT) Study: background and study design. Parle, M. and Samal M. K. Neuroprotective effects of pomegranate juice in mice. Hayouni, E. A., Miled, K., Boubaker, S., Bellasfar, Z., Abedrabba, M., Iwaski, H., Oku, H., Matsui, T., Limam, F., and Hamdi, M. Hydroalcoholic extract based-ointment from Punica granatum L. peels with enhanced in vivo healing potential on dermal wounds. studies show the hormones may raise your blood pressure, for instance. Cerda B, Soto C, Albaladejo MD, et al. J Nat Prod 2004;67:2096-8. Effect of extract of pomegranate (Punica granatum L.) on glycated protein-iron chelate-induced toxicity: an in vitro study on human umbilical-vein endothelial cells. The birth control pill may require a monthly cost or … View abstract. A. Aslam MN, Lansky EP, Varani J. Pomegranate as a cosmeceutical source: Pomegranate fractions promote proliferation and procollagen synthesis and inhibit matrix metalloproteinase-1 production in human skin cells. Surgery: Pomegranate might affect blood pressure. While these drugs were devised for controlling seizures, they are often very effective in stabilizing mood and have been called mood stabilizers for this reason. Drugs Exp.Clin.Res. Drinking pomegranate juice might decrease how quickly the liver breaks down rosuvastatin (Crestor). 2011;125(4):370-375. (flowers) on blood glucose level in normal and alloxan-induced diabetic rats. Gheflati A, Mohammadi M, Ramezani-Jolfaie N, Heidari Z, Salehi-Abargouei A, Nadjarzadeh A. A lung disease that makes it harder to breathe (chronic obstructive pulmonary disease or COPD). Harikrishnan, R., Heo, J., Balasundaram, C., Kim, M. C., Kim, J. S., Han, Y. J., and Heo, M. S. Effect of traditional Korean medicinal (TKM) triherbal extract on the innate immune system and disease resistance in Paralichthys olivaceus against Uronema marinum. You should always speak with your doctor or health care professional before you start, stop, or change any prescribed part of your health care plan or treatment and to determine what course of therapy is right for you. McDougall, G. J., Ross, H. A., Ikeji, M., and Stewart, D. Berry extracts exert different antiproliferative effects against cervical and colon cancer cells grown in vitro. Exp.Dermatol. 2006;15(2):93-102. American-Eurasian Journal of Agricultural and Environmental Science 2010;9(3):273-281. 3 min read. If you do take daily birth control medication, especially in pill form, you may want to pay attention to the cues your body is sending you about the state of your gut flora. Posted on November 28, 2016 by admineditor. View abstract. A birth control pill alters the balance between the various reproductive hormones in a woman’s body. J Med Food 2004;7:305-8. Rasheed, Z., Akhtar, N., and Haqqi, T. M. Pomegranate extract inhibits the interleukin-1beta-induced activation of MKK-3, p38alpha-MAPK and transcription factor RUNX-2 in human osteoarthritis chondrocytes. J.Sci.Food Agric. Georgian.Med News 2006;(140):78-83. Tayel, A. Kasimsetty, S. G., Bialonska, D., Reddy, M. K., Ma, G., Khan, S. I., and Ferreira, D. Colon cancer chemopreventive activities of pomegranate ellagitannins and urolithins. Contrary to what many people believe, the hormonal birth control pill does not hurt your future fertility, nor does it cause infertility. Grossmann, M. E., Mizuno, N. K., Schuster, T., and Cleary, M. P. Punicic acid is an omega-5 fatty acid capable of inhibiting breast cancer proliferation. J Herb Pharmacother 2006;6(2):79-92. The effects of pomegranate juice on the pharmacokinetics of simvastatin in healthy Korean subjects (PI-63). View abstract. How Taking Birth Control Pills Can Affect Women’s Mental Health ... “I went off of the birth control pill after being on it for a long time and I just felt like my world felt a little bit different,” Hill says. Braz.J.Biol. Drug Metab Dispos 2005;33:644-8. View abstract. View abstract. View abstract. Kafkas Üniversitesi. Well, this week, I want to shine the light on a little-known side effect of a prescription medication used by more than 10 million women in the U.S. CONDITIONS OF USE AND IMPORTANT INFORMATION: 10-28-2009;57(20):9427-9436. Z., Bao, L., He, R. R., and Kurihara, H. [Effect of pomegranate peel extracts on experimental prostatitis rats]. A. Hanley MJ, Masse G, Harmatz JS, et al. View abstract. 2008;30(3):183-193. Martin, K. R. Krueger C. G. Rodriquez G. Dreher M. and Reed J. D. Development of a novel pomegranate standard and new method for the quantitative measurement of pomegranate polyphenols. A RECENT REPORT from the U.S. Geological Survey (USGS) found that birth-control hormones excreted by women, flushed into waterways and eventually into drinking water can also impact fish fertility up to three generations after exposure — raising questions about their effects on humans, who are consuming the drugs without even knowing it in each glass of water they drink. J Agric Food Chem 2009;57(6):2550-7. Al-Mustafa, A. H. and Al-Thunibat, O. Y. Antioxidant activity of some Jordanian medicinal plants used traditionally for treatment of diabetes. J Nutr 2006;136(10):2481-2485. Most research shows that taking pomegranate products doesn't help with. View abstract. Arch Invest Med (Mex.) Xu, K. Z., Zhu, C., Kim, M. S., Yamahara, J., and Li, Y. Pomegranate flower ameliorates fatty liver in an animal model of type 2 diabetes and obesity. View abstract. Vet.Parasitol. Pharm.Biol. Health … Rosuvastatin (Crestor) is broken down by the body in the liver. View abstract. View abstract. J.Chromatogr.Sci. Parashar, A. Gupta C. Gupta S. K. and Kumar A. Antimicrobial ellagitannin from pomegranate (Punica granatum) fruits. Adhikari, A., Devkota, H. P., Takano, A., Masuda, K., Nakane, T., Basnet, P., and Skalko-Basnet, N. Screening of Nepalese crude drugs traditionally used to treat hyperpigmentation: in vitro tyrosinase inhibition. Samadloiy, H. R. Azizi M. H. and Barzegar M. Physico-chemical quality of seeds of pomegranate cultivars (Punica granatum L.) grown in Iran and antioxidative activity of their phenolic component. Bae, J. Y., Choi, J. S., Kang, S. W., Lee, Y. J., Park, J., and Kang, Y. H. Dietary compound ellagic acid alleviates skin wrinkle and inflammation induced by UV-B irradiation. Vitamins and Supplements to Avoid with Hepatitis C, Chronic obstructive pulmonary disease (COPD). A number of herbal remedies don't mix well with birth control pills. 2010;85(1):155-159. Antiviral Res. does cipro affect my birth control? Leiva, K. P., Rubio, J., Peralta, F., and Gonzales, G. F. Effect of Punica granatum (pomegranate) on sperm production in male rats treated with lead acetate. 2011;17(2):113-115. View abstract. Appl.Environ.Microbiol. View abstract. Farnsworth N, Bingel A, Cordell G, et al. AANA Journal 2008;76(5):373-374. Birth control pills are known to increase your body’s levels of natural melatonin, supplementing more melatonin on top of that may make those levels too high. Orak, H. H. Demirci A. S. and Gümüs T. Antibacterial and antifungal activity of pomegranate (Punica granatum L. View abstract. J.Agric.Food Chem. 2008;60(2):139-144. Some medications changed by the liver include amlodipine (Norvasc), diltiazem (Cardizem), verapamil (Verelan, Calan, others), indinavir (Crixivan), nelfinavir (Viracept), ritonavir (Norvir), saquinavir (Invirase), alfentanil (Alfenta), fentanyl (Sublimaze), midazolam (Versed), ondansetron (Zofran), propranolol (Inderal), and many others. Albrecht, M., Schneider, O., and Schmidt, A. Redox active donor-substituted punicin derivatives. Sundararajan, A., Ganapathy, R., Huan, L., Dunlap, J. R., Webby, R. J., Kotwal, G. J., and Sangster, M. Y. have many healthful effects, including a reduced risk for heart View abstract. Pomegranate juice supplementation to atherosclerotic mice reduces macrophage lipid peroxidation, cellular cholesterol accumulation and development of atherosclerosis. Ilbey, Y. O., Ozbek, E., Simsek, A., Cekmen, M., Somay, A., and Tasci, A. I. Even though “The Pill” may not be for everyone, probiotics definitely are! 2009;102(1):54-59. Free Radic Biol Med 2012;53(2):297-304. View abstract. View abstract. View abstract. Q. Pomegranate juice is supposed to be a health food, but There are many theories as to how antibiotics could potentially affect birth control, including: Antibiotics, such as the Z-Pack, are known to cause changes to our normal bacterial gut flora. Some women have claimed that CBD interferes with their birth control. Bishayee, A., Bhatia, D., Thoppil, R. J., Darvesh, A. S., Nevo, E., and Lansky, E. P. Pomegranate-mediated chemoprevention of experimental hepatocarcinogenesis involves Nrf2-regulated antioxidant mechanisms. Indian J.Pharm.Sci. 2011;25(11):1059-1066. J.Microbiol.Immunol.Infect. Elfalleh, W. Tlili N. Nasri N. Yahia Y. Hannachi H. Chaira N. Ying M. and Ferchichi A. Antioxidant Capacities of Phenolic Compounds and Tocopherols from Tunisian Pomegranate ( Punica granatum) Fruits. The effect of two methods of pomegranate (Punica granatum L) juice extraction on quality during storage at 4°C. Atherosclerosis 2010;208(1):119-125. View abstract. Sunburn. Menezes, S. M., Cordeiro, L. N., and Viana, G. S. Punica granatum (pomegranate) extract is active against dental plaque. 2010;75(7):C626-C632. Curr Urol Rep 2006;7:7. J Cardiovasc Pharmacol 2005;46:856-62. . women who take certain birth control pills may see a change in some of their blood fats that play a role in heart disease. Proceedings of the 11th Biennial Meeting of the Society for Free Radical Research International, 2002 Feb:1-9. Thank you! Paller CJ, Ye X, Wozniak PJ, et al. Jafri, M. A., Aslam, M., Javed, K., and Singh, S. Effect of Punica granatum Linn. Pomegranate juice and pomegranate extract do not impair oral clearance of flurbiprofen in human volunteers: divergence from in vitro results. Medications changed by the liver (Cytochrome P450 2D6 (CYP2D6) substrates) interacts with POMEGRANATE. View abstract. Abidov, M., Ramazanov, Z., Seifulla, R., and Grachev, S. The effects of Xanthigen in the weight management of obese premenopausal women with non-alcoholic fatty liver disease and normal liver fat. 2010;93(6):1957-1964. View abstract. Lai, S., Zhou, Q., Zhang, Y., Shang, J., and Yu, T. [Effects of pomegranate tannins on experimental gastric damages]. Progress in Modern Biomedicine 2008;8(11):2107-2108, 2125. But doesn't improve cycling time in competitive athletes. 10-14-2009;57(19):9197-9209. Birth control pills overall lower the risk of pregnancy and the risk of a fertilized egg implanting outside the uterus (ectopic pregnancy), which most often occurs in one of the tubes that carry eggs from the ovaries to the uterus (fallopian tubes). De, M., Krishna, De A., and Banerjee, A. Mem Inst Oswaldo Cruz 2002;97:1027-31. View abstract. View abstract. View abstract. View abstract. Effects of pomegranate juice on human cytochrome P450 2C9 and tolbutamide pharmacokinetics in rats. Hashemi, M., Kelishadi, R., Hashemipour, M., Zakerameli, A., Khavarian, N., Ghatrehsamani, S., and Poursafa, P. Acute and long-term effects of grape and pomegranate juice consumption on vascular reactivity in paediatric metabolic syndrome. Q. Pomegranate juice is supposed to be a health food, but I've heard that it can interfere with some medications, the way grapefruit juice can. 2008;19(12):848-855. 2010;9:208. If taking birth control changes the population of bacteria in your gut, and the bacteria in your gut affect your brain, then it stands to reason that taking birth control will also alter your brain. Electronic Journal of Environmental, Agricultural and Food Chemistry 2011;10(3):1958-1969. Nat.Prod.Res. Radjabian, T. Husseini H. F. Karami M. Rasooli I. and Faghihzadeh S. Effect of pomegranate fruit juice and seed oil on serum lipid levels and atherosclerosis development in hypercholesterolemic rabbits. Quintessence.Int. 2010;7(12):1473-1479. A randomized phase II study of pomegranate extract for men with rising PSA following initial therapy for localized prostate cancer. Das, A. K., Mandal, S. C., Banerjee, S. K., Sinha, S., Das, J., Saha, B. P., and Pal, M. Studies on antidiarrhoeal activity of Punica granatum seed extract in rats. View abstract. View abstract. View abstract. Consumption of pomegranate decreases serum oxidative stress and reduces disease activity in patients with active rheumatoid arthritis: a pilot study. Shukla, M., Gupta, K., Rasheed, Z., Khan, K. A., and Haqqi, T. M. Bioavailable constituents/metabolites of pomegranate (Punica granatum L) preferentially inhibit COX2 activity ex vivo and IL-1beta-induced PGE2 production in human chondrocytes in vitro. Before taking pomegranate talk to your healthcare provider if you take any medications that are changed by the liver.Some medications that are changed by the liver include amitriptyline (Elavil), codeine, desipramine (Norpramin), flecainide (Tambocor), fluoxetine (Prozac), ondansetron (Zofran), tramadol (Ultram), and others. Endo, E. H., Cortez, D. A., Ueda-Nakamura, T., Nakamura, C. V., and Dias Filho, B. P. Potent antifungal activity of extracts and pure compound isolated from pomegranate peels and synergism with fluconazole against Candida albicans. J.Investig.Allergol.Clin.Immunol. View abstract. View abstract. Life Extension 2008;14(5):18. J.Sci.Food Agric. Molluscicidal activity of Punica granatum bark and Canna indica root. Pomegranate seed oil in women with menopausal symptoms: a prospective randomized, placebo-controlled, double-blinded trial. The Harvard Medical School 6-Week Plan for Healthy Eating, Improving Memory: Understanding Age-Related Memory Loss. Heber D, Seeram NP, Wyatt H, et al. Int.J.Food Sci.Nutr. In: Fruits of warm climates. 2004;43(4):205-220. Panichayupakaranant, P. Tewtrakul S. and Yuenyongsawad S. Antibacterial, anti-inflammatory and anti-allergic activities of standardised pomegranate rind extract. Nat.Prod.Res. 1,2. Gonzalez-Ortiz M, Martinez-Abundis E, Espinel-Bermudez MC, Perez-Rubio KG. Bouroshaki, M. T., Sadeghnia, H. R., Banihasan, M., and Yavari, S. Protective effect of pomegranate seed oil on hexachlorobutadiene-induced nephrotoxicity in rat kidneys. How does the Birth Control Patch Work? Rock, W., Rosenblat, M., Miller-Lotan, R., Levy, A. P., Elias, M., and Aviram, M. Consumption of wonderful variety pomegranate juice and extract by diabetic patients increases paraoxonase 1 association with high-density lipoprotein and stimulates its catalytic activities. Isolates of methicillin-resistant Staphylococcus aureus growth and subsequent enterotoxin production sources of new antifertility agents I. 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